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Labro, Alain
One or more keywords matched the following items that are connected to Labro, Alain
Item TypeName
Concept Ion Channel Gating
Academic Article Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels.
Academic Article Modulation of HERG gating by a charge cluster in the N-terminal proximal domain.
Academic Article Role of the S6 C-terminus in KCNQ1 channel gating.
Academic Article KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain.
Academic Article Functional interactions between residues in the S1, S4, and S5 domains of Kv2.1.
Academic Article The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels.
Academic Article Quantitative single-cell ion-channel gene expression profiling through an improved qRT-PCR technique combined with whole cell patch clamp.
Academic Article Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues.
Academic Article Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel.
Academic Article The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure.
Academic Article A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics.
Academic Article Dual effect of phosphatidylinositol (4,5)-bisphosphate PIP(2) on Shaker K(+) [corrected] channels.
Academic Article Molecular mechanism for depolarization-induced modulation of Kv channel closure.
Academic Article The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking.
Academic Article Properties of deactivation gating currents in Shaker channels.
Academic Article The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state.
Academic Article Mutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel.
Academic Article Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening.
Academic Article Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore.
Academic Article Inverted allosteric coupling between activation and inactivation gates in K+ channels.
Academic Article The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels.
Academic Article Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient.
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  • Ion Channels